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San Antonio Drug Company
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At the southeast corner of St. Mary’s Street, the San Antonio Drug Company, for whom this building was erected, became the successor of two earlier drug companies: Dreiss, Thompson & Co. and Kalteyer & Schmidt, both established in the 1870s. A late 1990s renovation converted the building into a hotel.

Spanning the San Antonio River is the St. Mary’s Street Bridge, constructed in 1915. Architectural features include decorative swags and obelisk light posts.
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    San Antonio Drug Company
    200 S St Mary's St
    San Antonio, TX 78205

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